Top Active Series A Investors & VCs Funding Startups in the US in 2025

Last update to database: July 06, 2026

Leading Growth-Stage Investors & Venture Capital Firms Funding Series A Startups Across the US

Series A funding continues to define a critical growth stage for US startups in 2025, helping founders scale proven products and expand into new markets. The top active Series A investors and VCs funding startups in the US are backing companies in AI, SaaS, fintech, health tech, and climate tech—sectors attracting the most venture capital activity this year.


These investors specialize in transforming early traction into sustainable growth, providing the capital, strategic guidance, and networks startups need to reach Series B and beyond. Many are headquartered in San Francisco, New York, Austin, and Boston, while others are global firms actively funding Series A rounds across the United States.


Our database highlights investors currently funding and supporting Series A startups in the US. Updated weekly, it offers founders, analysts, and business-development teams real-time visibility into who’s actively investing at the growth-stage level across America.

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Comprehensive Database of Active Series A Investors & VCs Funding US Startups – Updated Weekly

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Investor Name
Industry Focus Recent Investments Recent Investment Date Check Size Stage Focus Geography Focus Company Headquarters Firm Type Portfolio Size Portfolio Highlights Co-Investor Network
Draper Associates Artificial Intelligence, Robotics & Automation, Biotechnology, Blockchain & Cryptocurrency, Aerospace & Space Subscribe to Unlock Subscribe to Unlock June, 2026 $250k-$500k Angel, Pre-Seed, Seed Global, United States San Mateo, California, United States Venture Capital 400 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Sequoia Capital, Founders Fund, Lightspeed Venture Partners, Accel
Spark Capital Enterprise Applications, Artificial Intelligence, Financial Services & FinTech, Web3 & Blockchain & Cryptocurrency, Marketplaces Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B United States, San Francisco, Boston, New York City San Francisco, California, United States Venture Capital 326 Subscribe to Unlock Subscribe to Unlock SV Angel, Tiger Global Management, SoftBank Vision Fund, Andreessen Horowitz
Union Square Ventures SaaS & Software, E-Commerce & Retail, Financial Services & FinTech, Artificial Intelligence, EdTech and Training Subscribe to Unlock Subscribe to Unlock June, 2026 $500k-$1M Pre-Seed, Seed, Series A, Series B, Series C, Series D United States New York, New York, United States Venture Capital 130 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Benchmark, Sequoia Capital, First Round Capital, Accel
Bain Capital Ventures Financial Services & FinTech, E-Commerce & Retail, Apps & Platforms, Artificial Intelligence, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B, Series C United States San Francisco, California, United States Venture Capital 400 Subscribe to Unlock Subscribe to Unlock Unknown
Paladin Capital Group Cyber Security & Privacy, Information Technology, SaaS & Software, Financial Services & FinTech, Government & Military Tech Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B United States, Europe Washington, District of Columbia, United States Venture Capital 65 Subscribe to Unlock Subscribe to Unlock Unknown
Khosla Ventures Artificial Intelligence, Health Care & Wellness, GreenTech & Sustainability, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock June, 2026 $1M–$10M Pre-seed, Seed, Series A, Series B, Growth United States, Global Menlo Park, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Founders Fund Artificial Intelligence, Biotechnology, Hardware, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock July, 2026 $1M-$10M Seed, Series A, Series B, Series C, Series D United States San Francisco, California, United States Venture Capital 90 Subscribe to Unlock Subscribe to Unlock Unknown
Felicis Artificial Intelligence, Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Security Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Pre-Seed, Seed, Series A United States, Canada, Australia, Brazil, Mexico, Ireland, Israel, Netherlands, Philippines, Singapore, France, Germany, United Kingdom, Armenia, Hong Kong, Bulgaria, Czech Republic, Estonia, Turkey, Finland Menlo Park, California, United States Venture Capital 200 Subscribe to Unlock Subscribe to Unlock Sequoia, Andreessen Horowitz, Accel, Benchmark Capital, Tiger Global
Castellan Group SaaS & Software, Health Care & Wellness, Artificial Intelligence, Financial Services & FinTech, Apps & Platforms Subscribe to Unlock Subscribe to Unlock June, 2026 $100k-$250k Seed, Series A United States Tempe, Arizona, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Andreessen Horowitz, Accel, Benchmark, Lightspeed Venture Partners
Town Hall Ventures Health Care & Wellness, Artificial Intelligence, SaaS & Software, Data & Analytics, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B United States, New York New York, New York, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, a16z, General Catalyst, Oak HC/FT, First Round Capital
First Round Capital Enterprise (mapped as Business & Professional Services), Artificial Intelligence, Hardware (mapped as Electronics & Devices), Health Care & Wellness, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock July, 2026 $1M–$10M Pre-seed, Seed, Series A United States San Francisco, California, United States Venture Capital 500 Subscribe to Unlock Subscribe to Unlock Unknown
Andreessen Horowitz Artificial Intelligence, Biotechnology, Blockchain & Cryptocurrency, Financial Services & FinTech, Gaming Subscribe to Unlock Subscribe to Unlock July, 2026 $500k–$1M Pre-seed, Seed, Series A, Series B, Growth, Late-stage North America, United States Menlo Park, California, United States Venture Capital 1000 Subscribe to Unlock Subscribe to Unlock Thrive Capital, General Catalyst, Alumni Ventures, Sequoia Capital, Accel
VMG Partners E-Commerce & Retail, Consumer Packaged Goods, Health Care & Wellness, SaaS & Software, Marketing, Advertising & Sales Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Series A, Series B, Series C United States, San Francisco San Francisco, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Unknown
Lerer Hippeau Apps & Platforms, SaaS & Software, Financial Services & FinTech, Health Care & Wellness, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock June, 2026 $100k-$1M Pre-Seed, Seed, Series A, Series B, Series C, Series D United States, New York New York City, New York, United States Venture Capital 350 Subscribe to Unlock Subscribe to Unlock Union Square Ventures, First Round Capital, Accel, Thrive Capital, Greycroft
Acrew Capital Business & Professional Services, Financial Services & FinTech, Information Technology, SaaS & Software, Enterprise Applications Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B United States, Mexico, Israel, Colombia, Indonesia Palo Alto, California, United States Venture Capital 140 Subscribe to Unlock Subscribe to Unlock Homebrew, Aspect Ventures, Y Combinator, Gaingels, Endeavor
S3 Ventures Business & Professional Services, Information Technology, Health Care & Wellness, Apps & Platforms, SaaS & Software Subscribe to Unlock Subscribe to Unlock June, 2026 $500k-$1M Seed, Series A, Series B United States, Texas, Austin Austin, Texas, United States Venture Capital 60 Subscribe to Unlock Subscribe to Unlock Unknown
Base10 Partners Financial Services & FinTech, SaaS & Software, Enterprise Applications, Artificial Intelligence, Business & Professional Services Subscribe to Unlock Subscribe to Unlock June, 2026 $1M–$10M Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 128 Subscribe to Unlock Subscribe to Unlock Tiger Global Management, Y Combinator, Andreessen Horowitz, SVB, Headline
Amplify Partners Artificial Intelligence, Cyber Security & Privacy, SaaS & Software, Financial Services & FinTech, Information Technology Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Pre-Seed, Seed, Series A United States, India, Canada, Israel, France Menlo Park, California, United States Venture Capital 157 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, DCVC, Tiger Global Management, Addition, Iconiq Capital
Homebrew Artificial Intelligence, SaaS & Software, Financial Services & FinTech, Health Care & Wellness, Data & Analytics Subscribe to Unlock Subscribe to Unlock June, 2026 $100k-$500k Pre-Seed, Seed, Series A United States Burlingame, California, United States Venture Capital 171 Subscribe to Unlock Subscribe to Unlock BoxGroup, Y Combinator, Google Ventures, Tiger Global Management
Upfront Ventures Health Care & Wellness, Artificial Intelligence, Biotechnology, Consumer Products, SaaS & Software Subscribe to Unlock Subscribe to Unlock June, 2026 $500k–$1M Pre-Seed, Seed, Series A United States, Europe, India, Israel Santa Monica, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Impellent Ventures SaaS & Software, Financial Services & FinTech, Healthcare & Wellness, Artificial Intelligence, Marketing, Advertising & Sales Subscribe to Unlock Subscribe to Unlock July, 2026 $500k-$1M Pre-Seed, Seed, Series A United States Rochester, New York, United States Venture Capital 14 Subscribe to Unlock Subscribe to Unlock NextView Ventures, Hubspot Ventures, Accomplice, BMC, Asymmetric Capital Partners
RA Capital Health Care & Wellness, Biotechnology, Medical Devices, Pharmaceuticals, Life Sciences Subscribe to Unlock Subscribe to Unlock July, 2026 $1M-$10M Seed, Series A, Series B, Series C North America, Europe, Asia Boston, Massachusetts, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Flagship Pioneering, Spark Capital, Perceptive Advisors, Bain Capital Life Science
Innovation Endeavors Artificial Intelligence, SaaS & Software, Biotechnology, Engineering, Hardware Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Pre-Seed, Seed, Series A United States, Israel Palo Alto, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Unknown
New Brunswick Innovation Foundation Technology, Digital Health, Cleantech, Innovation in SMEs Subscribe to Unlock Subscribe to Unlock June, 2026 $100k-$250k Pre-Seed, Seed Canada Fredericton, New Brunswick, Canada Venture Capital 40 Subscribe to Unlock Subscribe to Unlock MaRS Investment Accelerator Fund (IAF), BDC
BDC Artificial Intelligence, Biotechnology, Cleantech & Sustainability, Health Care & Wellness, SaaS & Software Subscribe to Unlock Subscribe to Unlock July, 2026 $100k-$10M Seed, Series A, Series B, Series C, Series D Canada Montreal, Quebec, Canada Venture Capital 2000 Subscribe to Unlock Subscribe to Unlock ApplyBoard, Borrowell, Ecobee, Hopper, Verafin
8VC Artificial Intelligence, Financial Services & FinTech, Health Care & Wellness, Logistics & Transportation, SaaS & Software Subscribe to Unlock Subscribe to Unlock June, 2026 $500k–$1M Pre-seed, Seed, Series A, Series B, Growth, Late-stage United States, San Francisco, Austin Austin, Texas, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock 9Yards Capital, Sequoia Capital, Andreessen Horowitz, Lightspeed, Founders Fund
Lux Capital High Tech, Enterprise Applications, Health Care & Wellness, Life Sciences, Enterprise Infrastructure Subscribe to Unlock Subscribe to Unlock June, 2026 $10M–$20M Seed, Series A United States, Canada, United Kingdom, Ghana, Ireland New York, New York, United States Venture Capital 280 Subscribe to Unlock Subscribe to Unlock Founders Fund, Y Combinator, Sequoia Capital, General Catalyst, Google Ventures
General Catalyst Artificial Intelligence, Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Enterprise Subscribe to Unlock Subscribe to Unlock June, 2026 $1M–$10M Seed, Series A, Series B, Growth North America, Europe, Asia Cambridge, Massachusetts, United States Venture Capital 800 Subscribe to Unlock Subscribe to Unlock GC Famiglia (community of CEOs, founders, partners, policymakers)
Obvious Ventures GreenTech & Sustainability, Health Care & Wellness, Food & Drink, SaaS & Software, Science & Engineering Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B United States, Europe San Francisco, California, United States Venture Capital 60 Subscribe to Unlock Subscribe to Unlock SOSV, Fifty Years, DBL Partners, Congruent Ventures
Madrona Artificial Intelligence, SaaS & Software, Health Care & Wellness, Apps & Platforms, Data & Analytics Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A, Series B, Series C United States, Seattle, Silicon Valley Seattle, Washington, United States Venture Capital 90 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, First Round Capital, Floodgate, BAMCAP
Wing Venture Capital Artificial Intelligence, Data & Analytics, Autonomous apps & Platforms, Web3, Biotechnology Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Pre-Seed, Seed, Series A United States Palo Alto, California, United States Venture Capital 22 Subscribe to Unlock Subscribe to Unlock Y Combinator, Uncork Capital, Greylock, Tiger Global Management, Madrona Venture Group, Google Ventures
Detroit Venture Partners Enterprise Applications, High Tech, Consumer, Artificial Intelligence, SaaS & Software Subscribe to Unlock Subscribe to Unlock June, 2026 $500k-$1M Seed, Series A United States, Australia, Israel Detroit, Michigan, United States Venture Capital 91 Subscribe to Unlock Subscribe to Unlock Ludlow Ventures, Y Combinator, Techstars, Invest Detroit, Hyde Park Venture Partners
Abstract Biotechnology, Blockchain & Cryptocurrency, SaaS & Software, Financial Services & FinTech, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A United States San Francisco, California, United States Venture Capital 150 Subscribe to Unlock Subscribe to Unlock Unknown
Keyhorse Capital Apps & Platforms, Information Technology, SaaS & Software, Data & Analytics, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock May, 2026 $100k-$250k Pre-Seed, Seed, Series A United States, Kentucky Louisville, Kentucky, United States Venture Capital 600 Subscribe to Unlock Subscribe to Unlock Kentucky Science & Technology Corporation, Local Angel Networks, Regional VC Funds
Supernatural Ventures Food & Drink Subscribe to Unlock Subscribe to Unlock May, 2026 $100k-$250k Seed Europe, Spain Toledo, Ohio, United States Venture Capital 9 Subscribe to Unlock Subscribe to Unlock Unknown
VoLo Earth Ventures Energy, Mobility (sustainable physical and digital connection technologies), Buildings (smart, net-zero buildings and construction), Industry (industrial solutions via materials, energy, transportation) Subscribe to Unlock Subscribe to Unlock May, 2026 $1M–$10M Pre-Seed, Seed, Series A, Series B United States Snowmass Village, Colorado, United States Venture Capital 36 Subscribe to Unlock Subscribe to Unlock Unknown
MissionOG Financial Services & FinTech, Data & Analytics, SaaS & Software, Business & Professional Services, Software Subscribe to Unlock Subscribe to Unlock June, 2026 $5M-$10M Pre-Seed, Seed, Series A, Series B United States, Canada Philadelphia, Pennsylvania, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Curql Fund, Michigan Capital Network
Future Labs Capital Artificial Intelligence, Biotechnology, Education and Training, SaaS & Software, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock May, 2026 $500k-$1M Seed, Series A, Series B United States, Indiana Jeffersonville, Indiana, United States Venture Capital 10 Subscribe to Unlock Subscribe to Unlock Unknown
Meritech Capital Software, Information Technology, Health Care & Wellness, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock May, 2026 $20M+ Series A, Series B, Series C, Growth, Late-stage United States, Germany, Canada, France, Belgium, Singapore Palo Alto, California, United States Venture Capital 200 Subscribe to Unlock Subscribe to Unlock Mayfield Fund, DFJ, Versant Ventures, Salesforce Ventures, Greylock Partners
Laidlaw & Company Health Care & Wellness, Financial Services & FinTech, Biotechnology, SaaS & Software, Information Technology Subscribe to Unlock Subscribe to Unlock May, 2026 $10M-$20M Series A, Series B, Series C United States, Europe New York, New York, United States Venture Capital 10 Subscribe to Unlock Subscribe to Unlock Unknown
Redpoint Apps & Platforms, SaaS & Software, Information Technology, Financial Services & FinTech, Media & Content Creation Subscribe to Unlock Subscribe to Unlock June, 2026 $1M–$10M Seed, Series A, Growth North America, Asia, United States, China San Francisco, California, United States Venture Capital 465 Subscribe to Unlock Subscribe to Unlock undefined
Plural VC High Tech, Enterprise Applications, Life Sciences, Artificial Intelligence, SaaS & Software Subscribe to Unlock Subscribe to Unlock June, 2026 $1M-$10M Seed, Series A Europe, United Kingdom Washington, District of Columbia, United States Venture Capital 35 Subscribe to Unlock Subscribe to Unlock Tiny, LocalGlobe, Episode 1 Ventures, Global Founders Capital, Entrepreneur First
BFG Partners Food & Drink, Personal Care, Pet, Marketing, Consumer Products Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Seed, Series A United States Boulder, Colorado, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
Breyer Capital Artificial Intelligence, SaaS & Software, Financial Services & FinTech, Media & Content Creation, Cyber Security & Privacy Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Seed, Series A, Series B United States Austin, Texas, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Accel, Kleiner Perkins, Sequoia Capital, Andreessen Horowitz
KCRise Fund Supply Chain/Logistics, Automotive, GovTech, Financial Services & FinTech, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock May, 2026 $100k-$250k Pre-Seed, Seed, Series A United States, Kansas City Kansas City, Missouri, United States Venture Capital 48 Subscribe to Unlock Subscribe to Unlock Unknown
Beliade Consumer Partners Food & Drink, Beauty & Personal Care, Fashion & Apparel, E-Commerce & Retail, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Seed, Series A United States Nashville, Tennessee, United States Private Equity 50 Subscribe to Unlock Subscribe to Unlock Unknown
Ten Coves Capital Financial Services & FinTech, SaaS & Software, Business & Professional Services Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Seed, Series A, Series B United States Darien, Connecticut, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
Westlake BioPartners Biotechnology, Health Care & Wellness, Science & Engineering Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Series A, Series B, Series C, Series D United States, California, Los Angeles, Westlake Village Westlake Village, California, United States Venture Capital 20 Subscribe to Unlock Subscribe to Unlock Unknown
HubSpot SaaS & Software, Financial Services & FinTech, Artificial Intelligence, Apps & Platforms, Data & Analytics Subscribe to Unlock Subscribe to Unlock June, 2026 $500k-$1M Seed, Series A, Series B Global Boston, United States Corporate VC 40 Subscribe to Unlock Subscribe to Unlock CapitalG, Sequoia Capital, First Round Capital, BoxGroup, Meritech Capital
AP Ventures Energy, Transportation, Chemicals, CleanTech, Industrial Technology Subscribe to Unlock Subscribe to Unlock May, 2026 $1M-$10M Pre-Seed, Seed, Series A Europe, North America, South Africa London, England, United Kingdom Venture Capital 10 Subscribe to Unlock Subscribe to Unlock Gather Ventures, SLB, CEPSA, Chevron Technology Ventures, JERA Inc.

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