Updated List of Top Active Investors & VCs Based in the US in 2025

Last update to database: October 05, 2026

Leading Investors & Venture Capital Firms Headquartered in the United States

In 2025, the US continues to serve as the central hub for global venture capital and private investment activity. The top active investors and VCs based in the United States are leading the charge in funding innovation across every major sector—from AI and fintech to health tech, SaaS, and clean energy.


These US-headquartered firms operate from major centers like San Francisco, New York, and Boston, but their investment reach extends worldwide. They’re not just providing capital—they’re backing visionary founders and shaping the next generation of high-growth companies.


Our database highlights investors and venture capital firms headquartered in the US who are currently active in startup funding. Updated weekly, it’s the most comprehensive source for discovering the firms driving venture activity across the United States.

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Comprehensive Database of Active Investors & VCs Based in the US – Updated Weekly

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Investor Name
Industry Focus Recent Investments Recent Investment Date Check Size Stage Focus Geography Focus Company Headquarters Firm Type Portfolio Size Portfolio Highlights Co-Investor Network
Energy Impact Partners Energy, GreenTech & Sustainability, Science & Engineering, Manufacturing, Business & Professional Services Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B, Series C, Series D North America, Europe New York, New York, United States Venture Capital 60 Subscribe to Unlock Subscribe to Unlock BP Ventures, Microsoft, Various strategic corporate partners
Viewpoint Financial Services & FinTech, Real Estate, Health Care & Wellness, Artificial Intelligence, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Series B, Series C United States, New York New York, New York, United States Venture Capital 13 Subscribe to Unlock Subscribe to Unlock Bessemer Venture Partners, Eight Roads, Khosla Ventures, Primary Venture Partners, Upfront Ventures
Automotive Ventures Connectivity, Cybersecurity & Privacy, Artificial Intelligence, Energy, Logistics & Transportation Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Seed Global Atlanta, Georgia, United States Venture Capital 48 Subscribe to Unlock Subscribe to Unlock Unknown
HubSpot SaaS & Software, Financial Services & FinTech, Artificial Intelligence, Apps & Platforms, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Seed, Series A, Series B Global Boston, United States Corporate VC 40 Subscribe to Unlock Subscribe to Unlock CapitalG, Sequoia Capital, First Round Capital, BoxGroup, Meritech Capital
Differential Ventures Artificial Intelligence, SaaS & Software, Cyber Security & Privacy, Data & Analytics, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2026 $250k-$500k Pre-Seed, Seed United States, New York New York, New York, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
Mayfield Artificial Intelligence, Financial Services & FinTech, Health Care & Wellness, SaaS & Software, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2026 $1M–$10M Seed, Series A, Series B United States, India Menlo Park, California, United States Venture Capital 150 Subscribe to Unlock Subscribe to Unlock Unknown
SignalFire Health Care & Wellness, SaaS & Software, Cyber Security & Privacy, Artificial Intelligence, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2026 $1M-$10M Seed, Series A, Series B, Series C, Series D United States, San Francisco San Francisco, California, United States Venture Capital 600 Subscribe to Unlock Subscribe to Unlock Unknown
Flex Capital SaaS & Software, Financial Services & FinTech, Artificial Intelligence, Information Technology, Apps & Platforms Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Seed, Series A, Series B United States, San Francisco San Francisco, California, United States Venture Capital 180 Subscribe to Unlock Subscribe to Unlock CRV, Y Combinator, Accel
SPRIG Equity Health Care & Wellness, Medical Devices, Digital Health Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Series B, Series C, Series D United States United States Venture Capital 30 Subscribe to Unlock Subscribe to Unlock Unknown
2048 Ventures Vertical AI, Deep Tech, Health Care & Wellness, Biotechnology, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Pre-Seed, Seed United States, North America New York, New York, United States Venture Capital 70 Subscribe to Unlock Subscribe to Unlock Founder Collective, First Row Partners
The Lind Partners Biotechnology, Financial Services & FinTech, Energy, Manufacturing, Science & Engineering Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Series C, Post-IPO United States, North America New York, New York, United States Private Equity 31 Subscribe to Unlock Subscribe to Unlock Tasman Group, plus 2 others
SV Angel SaaS & Software, Artificial Intelligence, Financial Services & FinTech, Information Technology, Web & Internet Platforms Subscribe to Unlock Subscribe to Unlock September, 2026 $100k-$250k Seed, Series B United States San Francisco, California, United States Venture Capital 1406 Subscribe to Unlock Subscribe to Unlock 10D Ventures, Alumni Ventures, Capchase, Riviera Partners, Dapper Labs
Petra Capital Partners Business & Professional Services, Health Care & Wellness, Financial Services & FinTech, SaaS & Software, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2026 $10M-$20M Series A, Series B, Series C, Series D United States Nashville, Tennessee, United States Private Equity 30 Subscribe to Unlock Subscribe to Unlock T2 Systems, BP3 Global, Salveo Specialty Pharmacy, New Century Hospice, Specialty Care
Khosla Ventures Artificial Intelligence, Health Care & Wellness, GreenTech & Sustainability, SaaS & Software, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2026 $1M–$10M Pre-seed, Seed, Series A, Series B, Growth United States, Global Menlo Park, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
Crosslink Capital Business & Professional Services, SaaS & Software, Financial Services & FinTech, Information Technology, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2026 $1M–$10M Seed, Series A North America, United States, San Francisco, Menlo Park San Francisco, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Unknown
BoxGroup FinTech, SaaS & Software, Marketplaces, GreenTech & Sustainability, Developer Tools Subscribe to Unlock Subscribe to Unlock October, 2026 $500k–$1M Pre-Seed, Seed, Series A United States, New York, San Francisco New York, New York, United States Venture Capital 872 Subscribe to Unlock Subscribe to Unlock Unknown
Halogen Ventures Consumer Technology, SaaS & Software, Marketing, Advertising & Sales, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2026 $100k-$500k Pre-Seed, Seed, Series A United States, Los Angeles Los Angeles, California, United States Venture Capital 72 Subscribe to Unlock Subscribe to Unlock Unknown
Wing Venture Capital Artificial Intelligence, Data & Analytics, Autonomous apps & Platforms, Web3, Biotechnology Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Pre-Seed, Seed, Series A United States Palo Alto, California, United States Venture Capital 22 Subscribe to Unlock Subscribe to Unlock Y Combinator, Uncork Capital, Greylock, Tiger Global Management, Madrona Venture Group, Google Ventures
Together Information Technology, Health Care & Wellness, SaaS & Software, Science & Engineering, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Pre-Seed, Seed, Series A, Series B, Series C, Series D North America Bellevue, Washington, United States Family Office 40 Subscribe to Unlock Subscribe to Unlock Unknown
Soleus Capital Biotechnology, Health Care & Wellness, Diagnostics, Science & Engineering, Medical Devices Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Series A, Series B, Series C United States Greenwich, Connecticut, United States Private Equity 74 Subscribe to Unlock Subscribe to Unlock Unknown
Array Ventures Artificial Intelligence, Cyber Security & Privacy, Health Care & Wellness, Financial Services & FinTech, Manufacturing Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Seed, Series A, Series B United States San Francisco, California, United States Venture Capital 80 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Sequoia, Founders Fund, General Catalyst, Khosla Ventures
First Round Capital Enterprise (mapped as Business & Professional Services), Artificial Intelligence, Hardware (mapped as Electronics & Devices), Health Care & Wellness, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock October, 2026 $1M–$10M Pre-seed, Seed, Series A United States San Francisco, California, United States Venture Capital 500 Subscribe to Unlock Subscribe to Unlock Unknown
Updata Partners SaaS & Software, Business & Professional Services, Information Technology, Data & Analytics, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2026 $10M-$20M Series B, Series C, Series D United States Washington, District of Columbia, United States Private Equity 80 Subscribe to Unlock Subscribe to Unlock Unknown
Thin Line Capital Energy, GreenTech & Sustainability, Manufacturing Subscribe to Unlock Subscribe to Unlock September, 2026 $250k-$500k Seed United States, Pasadena Pasadena, California, United States Venture Capital 10 Subscribe to Unlock Subscribe to Unlock Unknown
Canaan FinTech, Health Care & Wellness, Enterprise SaaS, Biotechnology, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A United States, Africa, Latin America, India, Asia-Pacific, Europe, Canada, Israel, Australia, Middle East San Francisco, California, United States Venture Capital 819 Subscribe to Unlock Subscribe to Unlock Unknown
The Venture Collective Health Care & Wellness, Artificial Intelligence, Biotechnology, Aerospace & Defense, Sustainable Materials Subscribe to Unlock Subscribe to Unlock September, 2026 $250k-$500k Pre-Seed, Seed, Series A United States, United Kingdom New York, New York, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock World class entrepreneurs, business leaders, global network of founders
Correlation Ventures Advertising, Data & Analytics, GreenTech & Sustainability, Cyber Security & Privacy, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2026 $100k-$1M Pre-Seed, Seed, Series A, Series B, Series C, Series D United States San Francisco, California, United States Venture Capital 400 Subscribe to Unlock Subscribe to Unlock Unknown
Jump Crypto Blockchain & Cryptocurrency, Financial Services & FinTech, Information Technology, SaaS & Software, Business & Professional Services Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B United States, India, Latin America Chicago, Illinois, United States Venture Capital 20 Subscribe to Unlock Subscribe to Unlock Paradigm, Consensys, Certora, BitPanda, TRM
Ten Eleven Ventures Cyber Security & Privacy, Information Technology, Communication & IT, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B United States Burlingame, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Unknown
August Capital Information Technology, SaaS & Software, Data & Analytics, Financial Services & FinTech, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B, Series C United States, San Francisco Bay Area San Francisco, California, United States Venture Capital 75 Subscribe to Unlock Subscribe to Unlock Unknown
Next Coast Ventures Financial Services & FinTech, Venture Capital, SaaS & Software, Health Care & Wellness, Apps & Platforms Subscribe to Unlock Subscribe to Unlock September, 2026 $1M–$10M Seed, Series A, Series B, Growth United States, Austin, Texas Austin, Texas, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Renaissance Venture Capital, de Anda Capital, Unknown, Unknown
Focal Apps & Platforms, SaaS & Software, Information Technology, Artificial Intelligence, Data & Analytics Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$1M Pre-Seed, Seed United States, Canada San Francisco, California, United States Venture Capital 30 Subscribe to Unlock Subscribe to Unlock Unknown
Spark Capital Enterprise Applications, Artificial Intelligence, Financial Services & FinTech, Web3 & Blockchain & Cryptocurrency, Marketplaces Subscribe to Unlock Subscribe to Unlock October, 2026 $1M-$10M Seed, Series A, Series B United States, San Francisco, Boston, New York City San Francisco, California, United States Venture Capital 326 Subscribe to Unlock Subscribe to Unlock SV Angel, Tiger Global Management, SoftBank Vision Fund, Andreessen Horowitz
8VC Artificial Intelligence, Financial Services & FinTech, Health Care & Wellness, Logistics & Transportation, SaaS & Software Subscribe to Unlock Subscribe to Unlock October, 2026 $500k–$1M Pre-seed, Seed, Series A, Series B, Growth, Late-stage United States, San Francisco, Austin Austin, Texas, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock 9Yards Capital, Sequoia Capital, Andreessen Horowitz, Lightspeed, Founders Fund
Greenoaks SaaS & Software, Financial Services & FinTech, Artificial Intelligence, E-Commerce & Retail, Web & Internet Platforms Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B, Series C United States, Europe, Asia San Francisco, California, United States Venture Capital 80 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Andreessen Horowitz, Lightspeed Venture Partners, Tiger Global, Accel
AIX Ventures Artificial Intelligence, SaaS & Software, Apps & Platforms, Data & Analytics, E-Commerce & Retail Subscribe to Unlock Subscribe to Unlock September, 2026 $250k-$500k Pre-Seed, Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Darling Ventures, A Capital, LaunchPad, Bloomberg Beta, K9 Ventures
Accomplice VC SaaS & Software, Financial Services & FinTech, Blockchain & Cryptocurrency, Business & Professional Services, Artificial Intelligence Subscribe to Unlock Subscribe to Unlock September, 2026 $100k-$250k Angel, Pre-Seed, Seed, Series A United States, North America Boston, Massachusetts, United States Venture Capital 55 Subscribe to Unlock Subscribe to Unlock Archetype, Vinyl, Vibe, Wolfhead, Spearhead
Unity Partners Financial Services & FinTech, Business & Professional Services, SaaS & Software, Managed Professional Services, Home Services Subscribe to Unlock Subscribe to Unlock September, 2026 $10M-$20M Series C, Series D United States Dallas, Texas, United States Private Equity 40 Subscribe to Unlock Subscribe to Unlock Unknown
Chemistry SaaS & Software, Artificial Intelligence, Financial Services & FinTech, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Pre-Seed, Seed, Series A, Series B United States San Francisco, California, United States Venture Capital 100 Subscribe to Unlock Subscribe to Unlock Unknown
RA Capital Health Care & Wellness, Biotechnology, Medical Devices, Pharmaceuticals, Life Sciences Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B, Series C North America, Europe, Asia Boston, Massachusetts, United States Venture Capital 40 Subscribe to Unlock Subscribe to Unlock Flagship Pioneering, Spark Capital, Perceptive Advisors, Bain Capital Life Science
IQT Biotechnology, Artificial Intelligence, Microelectronics & Quantum, Hardware, Government & Military Tech Subscribe to Unlock Subscribe to Unlock September, 2026 $250k-$500k Seed, Series A, Series B North America, Europe, Asia-Pacific, United States Arlington, Virginia, United States Other 473 Subscribe to Unlock Subscribe to Unlock T. Rowe Price, New Enterprise Associates, Salesforce Ventures, Lux Capital, National Science Foundation
Sofinnova Investments Biotechnology, Health Care & Wellness, Life Sciences, Sustainability Tech, Enterprise Applications Subscribe to Unlock Subscribe to Unlock September, 2026 $10M-$20M Seed, Series A, Series B, Series C, Series D United States, France, United Kingdom, Denmark, Belgium Menlo Park, California, United States Venture Capital 158 Subscribe to Unlock Subscribe to Unlock MB Capital, Galion.exe, Orbimed, General Atlantic, Cormorant Asset Management
Counterpart Ventures SaaS & Software, Business & Professional Services, Enterprise Software, Data & Analytics, Information Technology Subscribe to Unlock Subscribe to Unlock September, 2026 $500k–$1M Pre-Seed, Seed, Series A, Series B United States San Francisco, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Unknown
Waterman Ventures SaaS & Software, Artificial Intelligence, Financial Services & FinTech, EdTech and Training, Health Care & Wellness Subscribe to Unlock Subscribe to Unlock October, 2026 $50k-$100k Angel, Pre-Seed, Seed, Series A, Series B United States, North America Manchester, New Hampshire, United States Venture Capital 1400 Subscribe to Unlock Subscribe to Unlock Andreessen Horowitz, Sequoia, Khosla, Accel
Hivemind Capital Blockchain & Cryptocurrency, Financial Services & FinTech, Artificial Intelligence, Gaming, SaaS & Software Subscribe to Unlock Subscribe to Unlock September, 2026 $500k-$10M Pre-Seed, Seed, Series A, Series B United States, Taiwan, South Korea, Singapore, Vietnam, Hong Kong New York, New York, United States Venture Capital 30 Subscribe to Unlock Subscribe to Unlock Unknown
NVIDIA Artificial Intelligence, Hardware, Data & Analytics, SaaS & Software, Science & Engineering Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B United States, North America, Europe, Asia Santa Clara, California, United States Corporate VC 120 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Andreessen Horowitz, Lightspeed Venture Partners, Accel Partners, Kleiner Perkins
Insight Partners SaaS & Software, Cyber Security & Privacy, Financial Services & FinTech, Health Care & Wellness, Information Technology Subscribe to Unlock Subscribe to Unlock October, 2026 $10M–$20M Series A, Series B, Growth, Late-stage United States, Europe, Israel New York, New York, United States Venture Capital 800 Subscribe to Unlock Subscribe to Unlock Sequoia Capital, Accel, Tiger Global Management, TCV
Las Olas Venture Capital SaaS & Software, Artificial Intelligence, Logistics & Transportation, Health Care & Wellness, Financial Services & FinTech Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed United States, Eastern United States Fort Lauderdale, Florida, United States Venture Capital 30 Subscribe to Unlock Subscribe to Unlock Bling Capital, Industry Ventures, Sweetwood Capital, Bling Capital, Industry Ventures
A* Capital SaaS & Software, Artificial Intelligence, Financial Services & FinTech, Apps & Platforms, Internet Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Pre-Seed, Seed, Series A United States, San Francisco San Francisco, California, United States Venture Capital 50 Subscribe to Unlock Subscribe to Unlock Founders Fund, Sequoia Capital, Andreessen Horowitz
Gutbrain Ventures Enterprise Applications, High Tech, Artificial Intelligence, Vertical SaaS, Enterprise Infrastructure Subscribe to Unlock Subscribe to Unlock September, 2026 $1M-$10M Seed, Series A, Series B, Series C United States, Canada Boston, Massachusetts, United States Venture Capital 68 Subscribe to Unlock Subscribe to Unlock PBJ Capital, Glasswing Ventures, Techstars, BITKRAFT Ventures, Arca

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