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Updated List of Top Active Investors & VCs Based in the US in 2025
Last update to database: May 25, 2026
Leading Investors & Venture Capital Firms Headquartered in the United States
In 2025, the US continues to serve as the central hub for global venture capital and private investment activity. The top active investors and VCs based in the United States are leading the charge in funding innovation across every major sector—from AI and fintech to health tech, SaaS, and clean energy.
These US-headquartered firms operate from major centers like San Francisco, New York, and Boston, but their investment reach extends worldwide. They’re not just providing capital—they’re backing visionary founders and shaping the next generation of high-growth companies.
Our database highlights investors and venture capital firms headquartered in the US who are currently active in startup funding. Updated weekly, it’s the most comprehensive source for discovering the firms driving venture activity across the United States.
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Updated List of Top Active Investors & VCs Based in the US in 2025
Last update to database: May 25, 2026
Subscribe to Unlock Active Startup Investors
Request AccessConnect with active investors funding startups in your region or industry. Subscribe to unlock full firm and contact data.
Leading Investors & Venture Capital Firms Headquartered in the United States
In 2025, the US continues to serve as the central hub for global venture capital and private investment activity. The top active investors and VCs based in the United States are leading the charge in funding innovation across every major sector—from AI and fintech to health tech, SaaS, and clean energy.
These US-headquartered firms operate from major centers like San Francisco, New York, and Boston, but their investment reach extends worldwide. They’re not just providing capital—they’re backing visionary founders and shaping the next generation of high-growth companies.
Our database highlights investors and venture capital firms headquartered in the US who are currently active in startup funding. Updated weekly, it’s the most comprehensive source for discovering the firms driving venture activity across the United States.
Comprehensive Database of Active Investors & VCs Based in the US – Updated Weekly
This data is delayed by 4 weeks. Subscribe for instant access to real-time funding rounds and contact data.
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Investor Name
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Industry Focus | Recent Investments | Recent Investment Date | Check Size | Stage Focus | Geography Focus | Company Headquarters | Firm Type | Portfolio Size | Portfolio Highlights | Co-Investor Network |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Redesign Health | Health Care & Wellness, Artificial Intelligence, SaaS & Software, Financial Services & FinTech, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C | United States | New York, New York, United States | Venture Capital | 70 | Subscribe to Unlock Subscribe to Unlock | Declaration Partners, Euclidean Capital, True North Advisors |
| Nexus Venture Partners | SaaS & Software, Apps & Platforms, Information Technology, Financial Services & FinTech, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Seed, Series A | United States, India | Menlo Park, California, United States | Venture Capital | 450 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Congruent Ventures | Energy, GreenTech & Sustainability, Hardware, SaaS & Software, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k–$1M | Pre-seed, Seed, Series A | United States, Canada | San Francisco, California, United States | Venture Capital | 58 | Subscribe to Unlock Subscribe to Unlock | Prelude Ventures, Climate Capital, DOE, National Science Foundation, Wellington |
| Great Circle Ventures | Food & Drink, AgriTech & Farming, Biotechnology, GreenTech & Sustainability, E-Commerce & Retail | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $100k-$250k | Pre-Seed, Seed | United States | New York, New York, United States | Venture Capital | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Cerberus Capital Management | Real Estate, Financial Services & FinTech, Supply Chain and Strategic Opportunities, Credit, Private Equity | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $20M+ | Series C, Series D | United States, Europe, Brazil, United Kingdom, India, China, Japan, Australia | New York, New York, United States | Private Equity | 300 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Norwest | Biotechnology, Financial Services & FinTech, SaaS & Software, Consumer Products, Information Technology | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | North America, India, Israel | Menlo Park, California, United States | Venture Capital | 700 | Subscribe to Unlock Subscribe to Unlock | Accel, Citius, Elevation Capital, General Catalyst |
| Wisconsin Alumni Research Foundation | Artificial Intelligence, Biotechnology, Health Care & Wellness, Science & Engineering, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $250k-$500k | Seed, Series A | United States, Wisconsin, Madison | Madison, Wisconsin, United States | Venture Capital | 50 | Subscribe to Unlock Subscribe to Unlock | Baird Capital, Venture Investors, Capital Resource Partners, Charterhouse Capital Partners |
| IA Ventures | Financial Services & FinTech, Advertising, Artificial Intelligence, SaaS & Software, Cyber Security & Privacy | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $250k-$500k | Pre-Seed, Seed, Series A | United States, New York | New York, New York, United States | Venture Capital | 146 | Subscribe to Unlock Subscribe to Unlock | Sequoia Capital, Andreessen Horowitz, Accel, First Round Capital, Bessemer Venture Partners |
| Buoyant Ventures | SaaS & Software, Artificial Intelligence, Energy, Climate Tech (use GreenTech & Sustainability), Food & Drink | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Seed, Series A, Series B | United States, Chicago/Midwest | Chicago, Illinois, United States | Venture Capital | 16 | Subscribe to Unlock Subscribe to Unlock | Techstars, 1000 Ocean Startups, Powerhouse Ventures |
| Service Provider Capital | Business & Professional Services, Financial Services & FinTech, SaaS & Software, Information Technology, Marketing, Advertising & Sales | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $100k-$250k | Seed, Series A | United States - Rocky Mountain, Midwest, New England, Southeast, Texas, Pacific Northwest | Golden, Colorado, United States | Venture Capital | 600 | Subscribe to Unlock Subscribe to Unlock | Institutional Venture Funds (specific names not publicly listed) |
| H.C. Wainwright & Co. | Biotechnology, Pharmaceuticals, Health Care & Wellness, Financial Services & FinTech, Scientific Research | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Series A, Series B, Series C | United States, North America | New York, New York, United States | Other | 10 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Tamarack Global | Artificial Intelligence, Aerospace, Data & Analytics, Energy, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Pre-Seed, Seed, Series A | United States | Greenwich, Connecticut, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | WorldQuant Ventures, Overmatch Ventures, Liquid 2 Ventures, FJ Labs |
| FoundersEdge | Artificial Intelligence, SaaS & Software, Health Care & Wellness, Marketing, Advertising & Sales | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $100k-$250k | Pre-Seed | United States, Massachusetts, Connecticut | Boston, Massachusetts, United States | Venture Capital | 58 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Centana Growth Partners | Financial Services & FinTech, Enterprise Software, Data & Analytics, Artificial Intelligence, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $10M-$20M | Series A, Series B, Series C, Series D | United States | New York, New York, United States | Venture Capital | 35 | Subscribe to Unlock Subscribe to Unlock | Great Hill Partners, Francisco Partners, Alphasense, AlphaSense, PSS Systems |
| SC Master Fund | Biotechnology, Artificial Intelligence, Financial Services & FinTech, Energy, Logistics & Transportation | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | United States, California, Southern California, Los Angeles, Orange County, San Diego | Corona del Mar, California, United States | Venture Capital | 7124 | Subscribe to Unlock Subscribe to Unlock | Section 32, Griffin Gaming Partners, Visionary Ventures, Miramar Digital Ventures, Riot Ventures |
| BroadLight Capital | Technology, Consumer, Media & Entertainment | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Series A, Series B, Series C | United States | New York, New York, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Bee Partners | Artificial Intelligence, Hardware, SaaS & Software, Enterprise AI Agents, DeepTech | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Pre-Seed, Seed | United States, San Francisco | San Francisco, California, United States | Venture Capital | 100 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| The K Funds | Information Technology, SaaS & Software, Health Care & Wellness, Consumer Products, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | United States | Los Angeles, California, United States | Private Equity | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| LG Technology Ventures | Artificial Intelligence, Mobility (categorized as Mobile Technology), Advanced Materials (categorized under Science & Engineering), Life Sciences (categorized under Biotechnology), 5G (categorized under Mobile Technology) | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | Silicon Valley, South Korea | Santa Clara, California, United States | Corporate VC | 80 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Focal | Apps & Platforms, SaaS & Software, Information Technology, Artificial Intelligence, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Pre-Seed, Seed | United States, Canada | San Francisco, California, United States | Venture Capital | 30 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| GM Ventures | Autonomous Vehicles, Artificial Intelligence, Energy, Manufacturing, Electronics & Devices | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$20M | Seed, Series A, Series B | United States | Warren, Michigan, United States | Corporate VC | 101 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Trinity Capital | Financial Services & FinTech, Business & Professional Services, Equipment Financing | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Series A, Series B, Series C, Series D | United States, Europe | Phoenix, Arizona, United States | Private Equity | 420 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Uncork Capital | SaaS & Software, Financial Services & FinTech, Health Care & Wellness, E-Commerce & Retail, Information Technology | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $100k-$250k | Seed, Series A | United States | San Francisco, California, United States | Venture Capital | 115 | Subscribe to Unlock Subscribe to Unlock | Accel, Sequoia Capital, First Round Capital, Tiger Global, Andreessen Horowitz |
| Atacama Ventures | Energy, SaaS & Software, Financial Services & FinTech, Aerospace & Defense, Health Care & Wellness | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $100k-$250k | Angel, Pre-Seed, Seed, Series A | United States | San Francisco, California, United States | Venture Capital | 47 | Subscribe to Unlock Subscribe to Unlock | FJ Labs, Mana Ventures, Shrug Capital, Tiger Global Management, Unshackled Ventures |
| Systemic Ventures | Artificial Intelligence, Blockchain & Cryptocurrency, Apps & Platforms, SaaS & Software, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $250k-$500k | Seed | North America, United States | New York, New York, United States | Venture Capital | 3 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Fulcrum Equity Partners | Health Care & Wellness, SaaS & Software, Business & Professional Services, Financial Services & FinTech, Technology-enabled Services | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $10M-$20M | Series B, Series C, Series D | United States | Atlanta, Georgia, United States | Private Equity | 40 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Ritual Capital | Artificial Intelligence, Biotechnology, Consumer, Developer Tools, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $100k-$500k | Pre-Seed, Seed | United States, San Francisco | San Francisco, California, United States | Venture Capital | 15 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Blockchain Capital | Blockchain & Cryptocurrency, Financial Services & FinTech, Information Technology, SaaS & Software, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B, Growth | North America, United States, San Francisco | San Francisco, California, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | a16z crypto, Pantera Capital, Sequoia Capital, Paradigm |
| Cornucopian Capital | Health Care & Wellness, Food & Drink, Biotechnology, Science & Engineering, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $250k-$500k | Pre-Seed, Seed, Series A, Series B | United States | Montclair, New Jersey, United States | Venture Capital | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| XYZ Venture Capital | Financial Services & FinTech, SaaS & Software, Health Care & Wellness, Artificial Intelligence, Enterprise Software | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $500k-$1M | Pre-Seed, Seed, Series A, Series B | United States | San Francisco, California, United States | Venture Capital | 140 | Subscribe to Unlock Subscribe to Unlock | Y Combinator, Techstars, 500 Global, Sequoia Capital, Alumni Ventures |
| Integrity Growth Partners | SaaS & Software, Information Technology, Business & Professional Services, Software, Tech-Enabled Services | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $10M-$20M | Series A, Series B, Series C | United States | Los Angeles, California, United States | Private Equity | 30 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| HighSage Ventures | SaaS & Software, Financial Services & FinTech, Business & Professional Services, Consumer, Data & Analytics | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | United States, Europe | Boston, Massachusetts, United States | Venture Capital | 40 | Subscribe to Unlock Subscribe to Unlock | Juniper Square, Addepar, Klaviyo, Lattice, Cherre |
| Bessemer | Artificial Intelligence, Biotechnology, Cyber Security & Privacy, Financial Services & FinTech, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M–$10M | Seed, Series A, Series B, Series C | North America, Europe, Israel, India | San Francisco, California, United States | Venture Capital | 390 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Footwork | Consumer technology, Enterprise technology, SaaS & Software, Artificial Intelligence, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A | United States, San Francisco | San Francisco, California, United States | Venture Capital | 21 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Founders Fund | Artificial Intelligence, Biotechnology, Hardware, SaaS & Software, Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Seed, Series A, Series B, Series C, Series D | United States | San Francisco, California, United States | Venture Capital | 90 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| PCV | Sports & Fitness Tech, Gaming, Entertainment | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $100k-$250k | Pre-Seed, Seed | United States | Atlanta, Georgia, United States | Venture Capital | 20 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Bison Ventures | Food & Drink, Manufacturing, SaaS & Software, GreenTech & Sustainability, Science & Engineering | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | United States, United Kingdom | San Francisco, California, United States | Venture Capital | 9 | Subscribe to Unlock Subscribe to Unlock | Iron Grey, Acre Venture Partners, Fall Line Capital, Viking Global Investors, Lux Capital |
| CRV | SaaS & Software, Financial Services & FinTech, Information Technology, Apps & Platforms, Enterprise Software | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Seed, Series A, Series B | United States | Palo Alto, California, United States | Venture Capital | 750 | Subscribe to Unlock Subscribe to Unlock | Sequoia Capital, Andreessen Horowitz, Accel, Benchmark, Greylock Partners |
| 11 Tribes Ventures | SaaS & Software, Artificial Intelligence, Financial Services & FinTech, Apps & Platforms, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$1.5M | Seed, Series A | United States, Chicago, Nashville, Atlanta | Chicago, Illinois, United States | Venture Capital | 39 | Subscribe to Unlock Subscribe to Unlock | Alumni Ventures, Everywhere Ventures, Lago Innovation Fund, Service Provider Capital, Techstars |
| Baruch Future Ventures | Energy, GreenTech & Sustainability, Biotechnology, Manufacturing, Science & Engineering | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | United States, San Francisco | San Francisco, California, United States | Venture Capital | 54 | Subscribe to Unlock Subscribe to Unlock | Energy Impact Partners, Breakthrough Energy Ventures, The Westly Group |
| Icon Ventures | Artificial Intelligence, Data & Analytics, Cyber Security & Privacy, Health Care & Wellness, SaaS & Software | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Seed, Series A, Series B | United States | Palo Alto, California, United States | Venture Capital | 110 | Subscribe to Unlock Subscribe to Unlock | Sequoia Capital, Andreessen Horowitz, Accel, Lightspeed Venture Partners |
| Acrew Capital | Business & Professional Services, Financial Services & FinTech, Information Technology, SaaS & Software, Enterprise Applications | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Seed, Series A, Series B | United States, Mexico, Israel, Colombia, Indonesia | Palo Alto, California, United States | Venture Capital | 140 | Subscribe to Unlock Subscribe to Unlock | Homebrew, Aspect Ventures, Y Combinator, Gaingels, Endeavor |
| SOSV | Biotechnology, Hardware, Artificial Intelligence, Food & Drink, GreenTech & Sustainability | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $500k-$1M | Pre-Seed, Seed, Series A | North America, Asia, Europe | Princeton, New Jersey, United States | Venture Capital | 1000 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Better Ventures | SaaS & Software, Artificial Intelligence, Biotechnology, GreenTech & Sustainability, Food & Drink | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Pre-Seed, Seed | United States | Oakland, California, United States | Venture Capital | 119 | Subscribe to Unlock Subscribe to Unlock | Gaingels, 6Climate Capital, SOSV, IndieBio, Plug and Play Tech Center |
| Soleus Capital | Biotechnology, Health Care & Wellness, Diagnostics, Science & Engineering, Medical Devices | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Series A, Series B, Series C | United States | Greenwich, Connecticut, United States | Private Equity | 74 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| QED Investors | Financial Services & FinTech | Subscribe to Unlock Subscribe to Unlock | May, 2026 | $1M-$10M | Pre-Seed, Seed, Series A, Series B, Series C, Series D | North America, Europe, Latin America, Asia, Africa | Alexandria, Virginia, United States | Venture Capital | 225 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Standard Capital | Artificial Intelligence, SaaS & Software, Business & Professional Services | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Series A | United States, San Francisco | San Francisco, California, United States | Venture Capital | 2 | Subscribe to Unlock Subscribe to Unlock | Y Combinator, Ali Rowghani, Paul Buchheit, Paul Graham, SV Angel |
| Presidio Ventures | Enterprise IT, Cybersecurity & Privacy, Artificial Intelligence, Digital Media, Mobility | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Seed, Series A, Series B, Series C | United States | Santa Clara, California, United States | Corporate VC | 200 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| 5IR Funds | Artificial Intelligence, Blockchain & Cryptocurrency, Quantum Computing, Advanced Materials, Virtual Reality | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $1M-$10M | Pre-Seed, Seed, Series A | United States | Plano, Texas, United States | Venture Capital | 25 | Subscribe to Unlock Subscribe to Unlock | Unknown |
| Initialized Capital | Enterprise SaaS, Sustainability, Health Care & Wellness, Hard Tech, Artificial Intelligence | Subscribe to Unlock Subscribe to Unlock | April, 2026 | $500k-$1M | Seed | United States | San Francisco, California, United States | Venture Capital | 175 | Subscribe to Unlock Subscribe to Unlock | Y Combinator, Tiger Global Management, SV Angel, Seven Seven Six |
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